Using molecular-beam-epitaxy growth techniques, we have synthesized ferroma
gnet/insulator/ferromagnet trilayer heterostructures with the "colossal" ma
gnetoresistance material La1-xSrxMnO3 as the ferromagnet. These trilayer fi
lms were fabricated into magnetic tunnel junctions which exhibit magnetores
istance Delta R/R(H) of as much as 450% in 200 Oe applied field at 14 K, an
d which persists up to similar to 250 K. In situ reflection high-energy ele
ctron diffraction (RHEED) allows us to correlate the quality of the epitaxi
al growth with the magnetoresistive properties. Samples which showed signs
of disorder in RHEED also exhibit disorder effects in low-temperature trans
port and have smaller magnetoresistance which vanishes at lower temperature
s. (C) 2000 American Institute of Physics. [S0003-6951(00)01014-7].