Although the knowledge exists to relieve cancer pain, inadequate pain relie
f persists as an international health problem. The World Health Organizatio
n has recommended a threefold strategy to improve cancer pain management: h
ealth policy, drug availability, and education. Yet major barriers to effec
tive cancer pain management exist in every country of the world. Effective
strategies to improve pain management must be based on an understanding of
the issues in individual countries. This report evaluates cultural and othe
r factors influencing cancer pain management in the Republic of South Afric
a. This ethnographic field study included multiple methods of data collecti
on: analysis of documents, participant observation, focused interviews, and
in-depth interviews of informants (n = 33) who represented multiple stakeh
olders in a variety of settings. Cultural beliefs and practices form the co
ntext for understanding cancer pain and how it is managed. Cultural variabi
lity exists regarding cancer as a disease, pain expectations, pain toleranc
e, pain expression, and health care practices. Key factors that influence h
ow pain is managed included standards, knowledge, resources, communication
and the patient-provider relationship, and teamwork and professional relati
onships. The existence of these factors promotes effective pain management,
whereas their absence creates a barrier to achieving this aim.