The fungal GATA factors

The DNA-binding domains of eucaryotic GATA factors comprise a four-cysteine Zn finger and an adjacent basic region. Fungal GATA factors regulate nitro gen metabolism, light induction, siderophore biosynthesis and mating-type s witching. Hydrophobic interactions determine binding-site specificity, inte ractions with other factors may determine promoter specificity One GATA fac tor has recently been shown to determine a drastic chromatin rearrangement.