Intra-hepatic portal hypertension during chronic lymphatic leukemia

Authors
Pauwels, M Pauwels, S Capron, JP Sevestre, H Desablens, B
Citation
M. Pauwels et al., Intra-hepatic portal hypertension during chronic lymphatic leukemia, GASTRO CL B, 24(2), 2000, pp. 221-224
Citations number
17
Categorie Soggetti
Gastroenerology and Hepatology","da verificare
Journal title
GASTROENTEROLOGIE CLINIQUE ET BIOLOGIQUE
ISSN journal
03998320 → ACNP
Volume
24
Issue
2
Year of publication
2000
Pages
221 - 224
Database
ISI
SICI code
0399-8320(200002)24:2<221:IPHDCL>2.0.ZU;2-U
Abstract
Portal hypertension in chronic lymphocytic leukemia is rare. A 66 year-old man was admitted for splenomegaly, thrombopenia and cholestasis. Endoscopy showed esophageal varices. The hepatic venous pressure gradient was 15 mmHg . The liver biopsy showed dense leukemia cells in sinusoidal and portal sit es. After splenectomy, the hepatic venous pressure gradient normalized but esophageal varices and cholestasis persisted. The authors discuss the mecha nisms of portal hypertension in chronic lymphocytic leukemia. Previously re ported cases are summarized.