S. Hiraishi et al., Transthoracic ultrasonic visualisation of coronary aneurysm, stenosis, andocclusion in Kawasaki disease, HEART, 83(4), 2000, pp. 400-405
Citations number
20
Categorie Soggetti
Cardiovascular & Respiratory Systems","Cardiovascular & Hematology Research
Objective-To determine the sensitivity and specificity of our transthoracic
echocardiographic technique using high frequency (7.5 MHz) transducers for
identification of the presence and type of coronary artery disease in pati
ents with Kawasaki disease.
Design-The results of the prospective echocardiographic study in each of se
ven segments of the four major coronary arteries were compared with the sel
ective coronary angiograms.
Setting-Kitasato University Hospital.
Subjects-60 patients with Kawasaki disease, ranging in age from 8.0 months
to 22 years (median, 6.0 years).
Results-Adequate echocardiographic images were obtained in 397 (95%) of 420
coronary segments. Coronary angiography showed the presence of coronary an
eurysms in 87 segments and stenosis or occlusion in 28. The overall sensiti
vity and specificity of cross sectional echocardiography for correctly iden
tifying coronary aneurysms were 95% and 99%, respectively; for correctly id
entifying coronary stenosis or occlusion the values were 85% and 98% for th
e right coronary artery, and 80% and 97% for the left anterior descending c
oronary artery Agreement on the presence or absence of coronary aneurysms a
nd obstructive lesions on echocardiograms between the two observers was 1.0
and 0.98, respectively.
Conclusions-Echocardiography may provide a non-invasive means of identifyin
g the presence and type of coronary artery disease in patients with Kawasak
i disease.