Objective: There is evidence that burnout may be a clinical entity with pat
hological stress reaction features related to the inability in finding plea
sure from work. The purpose of this study was to investigate the relationsh
ip between burnout and depression. Methods: The study took place in the gen
eral hospital AHEPA of Thessaloniki. All members of the nursing staff(in to
tal 368 subjects) took part. The protocol was self-reported and anonymous,
in order to obtain as valid data as possible and included the Maslach Burno
ut Inventory (MBI) to assess the level of burnout, the Eysenck Personality
Questionnaire (EPQ) to assess personality traits, and the Zung Self-Rating
Depression Scale to assess depressive symptomatology. Results: The analysis
revealed a weak but significant relationship between burnout and depressio
n. Conclusions: Depression is a pervasive disorder that affects almost ever
y aspect of the patient's life. On the contrary, burnout is, by definition,
a syndrome restricted to the patient's professional environment. However,
it seems that there may be two distinct types of burnout syndromes, of whic
h the one comprising the majority of nurses has little or no common feature
s with depression. The second type consists of individuals with a predispos
ition to develop burnout. The latter is characterized by more severe sympto
matology, phenotypic similarity to depression and presumably common etiolog
ical mechanisms.