Arisostatins A and B, new members of tetrocarcin class of antibiotics fromMicromonospora sp TP-A0316 - I. Taxonomy, fermentation, isolation and biological properties

Authors
Furumai, T Takagi, K Igarashi, Y Saito, N Oki, T
Citation
T. Furumai et al., Arisostatins A and B, new members of tetrocarcin class of antibiotics fromMicromonospora sp TP-A0316 - I. Taxonomy, fermentation, isolation and biological properties, J ANTIBIOT, 53(3), 2000, pp. 227-232
Citations number
12
Categorie Soggetti
Microbiology
Journal title
JOURNAL OF ANTIBIOTICS
ISSN journal
00218820 → ACNP
Volume
53
Issue
3
Year of publication
2000
Pages
227 - 232
Database
ISI
SICI code
0021-8820(200003)53:3<227:AAABNM>2.0.ZU;2-P
Abstract
Arisostatins A and B, new members of tetrocarcin class of antibiotics were isolated from the culture broth of an actinomycete strain. The producing st rain, TP-A0316, was identified as Micromonospora sp. Arisostatins were obta ined from the culture fluid by solvent extraction and chromatographic purif ication. They showed antibiotic activity against Gram-positive bacteria and antitumor activity.