A Bacillus subtilis gene of previously unknown function, yhaG, is translationally regulated by tryptophan-activated TRAP and appears to be involved in tryptophan transport
Jp. Sarsero et al., A Bacillus subtilis gene of previously unknown function, yhaG, is translationally regulated by tryptophan-activated TRAP and appears to be involved in tryptophan transport, J BACT, 182(8), 2000, pp. 2329-2331
Computer analysis of the Bacillus subtilis genome sequence revealed a gene
with no previously attributed function, yhaG, specifying a transcript conta
ining a presumptive binding site for the tryptophan-activated regulatory pr
otein, TRAP. The presumptive TRAP binding site overlaps the yhaG Shine-Dalg
arno sequence and translation initiation region. TRAP was shown to regulate
expression of yhaG translationally. Production of the yhaG transcript in v
ivo was found to compete for the binding of TRAP to other known TRAP bindin
g sites. YhaG is likely to be a transmembrane protein involved in tryptopha
n transport.