Ca. Clayton et al., National Human Exposure Assessment Survey (NHEXAS): distributions and associations of lead, arsenic and volatile organic compounds in EPA Region 5, J EXP AN EN, 9(5), 1999, pp. 381-392
Citations number
7
Categorie Soggetti
Environment/Ecology
Journal title
JOURNAL OF EXPOSURE ANALYSIS AND ENVIRONMENTAL EPIDEMIOLOGY
The National Human Exposure Assessment Survey (NHEXAS) Phase I field study
conducted in EPA Region 5 provides extensive exposure data on approximately
250 study participants selected via probability sampling. Associated envir
onmental media and biomarker (blood, urine) concentration data were also ob
tained to aid in the understanding of relationships of the exposures to bot
h contaminant sources and doses. Distributional parameters for arsenic (As)
, lead (Pb), and four volatile organic compounds (VOCs)-benzene, chloroform
, tetrachloroethylene, and trichloroethylene-were estimated for each of the
relevant media using weighted data analysis techniques. Inter-media associ
ations were investigated through correlation analysis, and longitudinal cor
relations and models were used to investigate longitudinal patterns. Solid
food appeared to be a major contributor to urine As levels, while Pb levels
in household (HH) dust, personal air, and beverages all were significantly
associated with blood Pb levels. Relatively high (>0.50) longitudinal corr
elations were observed for tap water Pb and As, as compared to only moderat
e longitudinal correlations for the personal air VOCs.