COMPARISON OF HUMAN AND MURINE ISOLATES OF SCHISTOSOMA-MANSONI FROM RICHARD-TOLL, SENEGAL, BY ISOELECTRIC-FOCUSING

Studies on human and murine isolates of Schistosoma mansoni, from Rich ard-Toll, Senegal, were carried out by isoelectric focusing in polyacr ylamide gels. Seven enzyme systems; lactate dehydrogenase (LDH), malat e dehydrogenase (MDH), glucose-6-phosphate dehydrogenase (G6PD), acid phosphatase (AcP), hexokinase (HK), glucose phosphate isomerase (GPI), and phosphoglucomutase (PGM), were used to compare the two isolates. AU systems tested, apart from LDH, were found to be polymorphic for bo th isolates. Interestingly, one phenotype is more frequent than the re mainder. The results show that there is no significant genetic variati on between the S. mansoni isolates from man and the rodents, Arvicanth is niloticus and Mastomys huberti.