Quality of care when dealing with a multiresistant bacteria infection in the Dijon university hospital.

Objective - Preventing the spread of multiresistant bacteria is largely rel ated to the observance of standard precautions, the isolation of infected p atients, and the controlled use of antibiotics. A survey was performed on t he qualify of antibiotic therapy and isolation of patients infected by mult iresistant bacteria. Material and method-A committee was set up grouping representatives from th e Infectious Disease department, and the Epidemiology and Hygiene departmen t This committee set out criteria for an adequate isolation. Bacteriologica l data and clinical details were matched with antibiotic prescriptions to d etermine the validity of the latter. Results - The committee noted an adequate isolation in 39% of the cases. An tibiotic therapy was adequate in 64% of the cases. The main source of inade quate therapy was a poor knowledge of the pharmacokinetic properties of ant ibiotics (18%), the absence of reevaluation after antibiogram results (13.5 %), and inadequate drug association (10.8%). Conclusion - This investigation should allow us to define a clear policy so as to prevent the development of multiresistant bacteria. (C) 2000 Edition s scientifiques et medicales Elsevier SAS.