The role of dendritic cells in the innate immune system

Authors
Clark, GJ Angel, N Kato, M Lopez, JA MacDonald, K Vuckovic, S Hart, DNJ
Citation
Gj. Clark et al., The role of dendritic cells in the innate immune system, MICROBES IN, 2(3), 2000, pp. 257-272
Citations number
166
Categorie Soggetti
Immunology
Journal title
MICROBES AND INFECTION
ISSN journal
12864579 → ACNP
Volume
2
Issue
3
Year of publication
2000
Pages
257 - 272
Database
ISI
SICI code
1286-4579(200003)2:3<257:TRODCI>2.0.ZU;2-Z
Abstract
Dendritic cells (DCs) are bone-marrow-derived leucocytes that are specialis ed antigen presenting cells capable of stimulating a primary T-lymphocyte r esponse to specific antigen. In this chapter we discuss the role DCs play i n the innate response acting as a critical link with the adaptive response and the influence of the innate response on dendritic cells. (C) 2000 Editi ons scientifiques et medicales Elsevier SAS.