Antigenic variation in the persistence and transmission of the ehrlichia Anaplasma marginale

Authors
Palmer, GH Brown, WC Rurangirwa, FR
Citation
Gh. Palmer et al., Antigenic variation in the persistence and transmission of the ehrlichia Anaplasma marginale, MICROBES IN, 2(2), 2000, pp. 167-176
Citations number
50
Categorie Soggetti
Immunology
Journal title
MICROBES AND INFECTION
ISSN journal
12864579 → ACNP
Volume
2
Issue
2
Year of publication
2000
Pages
167 - 176
Database
ISI
SICI code
1286-4579(200002)2:2<167:AVITPA>2.0.ZU;2-B
Abstract
Tick-borne transmission of ehrlichial pathogens requires rickettsemic reser voir hosts to maintain a population of infected vectors. Persistence in the ir respective mammalian hosts appears to be a common feature of the tick-tr ansmitted ehrlichiae. How infection persists in immunocompetent hosts is un known. In this review, we describe studies on Anaplasma marginale, an ehrli chial pathogen of cattle, that support antigenic variation as a primary mec hanism of persistence. (C) 2000 Editions scientifiques et medicales Elsevie r SAS.