Turning a corner on HIV neutralization?

Authors
Nunberg, JH Follis, KE Trahey, M LaCasse, RA
Citation
Jh. Nunberg et al., Turning a corner on HIV neutralization?, MICROBES IN, 2(2), 2000, pp. 213-221
Citations number
90
Categorie Soggetti
Immunology
Journal title
MICROBES AND INFECTION
ISSN journal
12864579 → ACNP
Volume
2
Issue
2
Year of publication
2000
Pages
213 - 221
Database
ISI
SICI code
1286-4579(200002)2:2<213:TACOHN>2.0.ZU;2-Q
Abstract
HIV vaccine development has been hampered by the inability of conventional immunogens to elicit antibodies capable of neutralizing primary isolates of the virus. Recent studies using 'fusion-competent' immunogens that capture transitional intermediate structures of the functioning envelope protein s uggest that this goal may now be achievable. (C) 2000 Editions scientifique s et medicales Elsevier SAS.