Oct-4, scene 1: the drama of mouse development

Authors
Stewart, CL
Citation
Cl. Stewart, Oct-4, scene 1: the drama of mouse development, NAT GENET, 24(4), 2000, pp. 328-330
Citations number
10
Categorie Soggetti
Molecular Biology & Genetics
Journal title
NATURE GENETICS
ISSN journal
10614036 → ACNP
Volume
24
Issue
4
Year of publication
2000
Pages
328 - 330
Database
ISI
SICI code
1061-4036(200004)24:4<328:OS1TDO>2.0.ZU;2-Z
Abstract
A study by Niwa et al. shows that changes in the levels of the transcriptio n factor Oct-4 regulate the differentiation of embryonic stem cells along t hree different pathways. These observations suggest a possible mechanism by which Oct-4 determines the formation of the mouse pre-implantation embryo.