Although alexithymia is found in patients with various somatic disorders, i
t remains unclear whether it is really related to organic disease - as prop
osed by the founders of the concept.[125]. As the interplay between the exp
erience of emotion and possible adverse effects on health is a fundamental
tenet of psychosomatic medicine, alexithymia remains an interesting concept
to be further explored,especially concerning (1) possible pathways linking
emotion to physical illness and (2) the neurobiologic basis of emotional i
nformation processing. Compared to the intense international discussion on
the subject, in Germany there are still many doubts concerning alexithymia:
while some clinicians question the validity of the whole concept, psychiat
ric and psychosomatic researchers seem unsure about alexithymia's role in t
heir search for a physiological basis to the link between emotion and physi
cal disease. Our review deals with the empirical literature concerning that
possible association and tries to tie in their data with modern, neurobiol
ogically founded insights into emotional information processing within the
brain.