Treatment of acute disseminated encephalomyelitis with intravenous immunoglobulin

Authors
Sahlas, DJ Miller, SP Guerin, M Veilleux, M Francis, G
Citation
Dj. Sahlas et al., Treatment of acute disseminated encephalomyelitis with intravenous immunoglobulin, NEUROLOGY, 54(6), 2000, pp. 1370-1372
Citations number
10
Categorie Soggetti
Neurology,"Neurosciences & Behavoir
Journal title
NEUROLOGY
ISSN journal
00283878 → ACNP
Volume
54
Issue
6
Year of publication
2000
Pages
1370 - 1372
Database
ISI
SICI code
0028-3878(20000328)54:6<1370:TOADEW>2.0.ZU;2-G
Abstract
Acute disseminated encephalomyelitis (ADEM) is a presumed immune-mediated, demyelinating disease of the CNS for which the standard treatment is high-d ose steroids. We describe two patients with ADEM in whom treatment with IV methylprednisolone coincided with deterioration in their clinical status. T hey were subsequently treated with IV immunoglobulin and exhibited dramatic clinical improvement, with return to their previous level of functioning.