An experimental set-up for irradiation of biological material with low-ener
getic and low-mass ions in an external beam has been designed using the cyc
lotron U-120 of the Rossendorf Research Centre. The horizontal beam line co
nsists of components for beam spread our and control, for particle spectros
copy and monitoring and for energy and dose rate variation. To prove the pe
rformance of the beam line, a first radiobiological experiment has been car
ried out by exposing of R1 fish liver cells to 8.2 MeV protons. (C) 2000 El
sevier Science B.V. All rights reserved.