Pt(Me-Duphos)-catalyzed asymmetric hydrophosphination of activated olefins: Enantioselective synthesis of chiral phosphines

Authors
Kovacik, I Wicht, DK Grewal, NS Glueck, DS Incarvito, CD Guzei, IA Rheingold, AL
Citation
I. Kovacik et al., Pt(Me-Duphos)-catalyzed asymmetric hydrophosphination of activated olefins: Enantioselective synthesis of chiral phosphines, ORGANOMETAL, 19(6), 2000, pp. 950-953
Citations number
25
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
ORGANOMETALLICS
ISSN journal
02767333 → ACNP
Volume
19
Issue
6
Year of publication
2000
Pages
950 - 953
Database
ISI
SICI code
0276-7333(20000320)19:6<950:PAHOAO>2.0.ZU;2-D
Abstract
Platinum-catalyzed asymmetric hydrophosphination of activated olefins using the catalyst precursor Pt(R,R-Me-Duphos)(trans-stilbene) (1) gives chiral phosphines with control of stereochemistry at phosphorus or carbon centers, Stoichiometric reactions of 1 allow observation of P-H oxidative addition diastereoselective olefin insertion, and reductive elimination steps, which make up the proposed catalytic cycle.