There are few reports about magnetic resonance cholangiopancreatography (MR
CP) in cystic lesions of the pancreas (KLP). For this reason, we have under
taken a prospective study evaluating the diagnostic efficiency of MRCP as c
ompared with ultrasonography. Twenty-four patients with KLP were examined w
ith magnetic resonance imaging (MRI), and standard and cholangiopancreatogr
aphy. There were seven cases of cysts associated with acute pancreatitis, 1
1 patients with KLP and chronic calcifying pancreatitis, five cases of cyst
ic neoplasms of the pancreas, and one polycystic disease of the gland. All
cases were first submitted to ultrasonography, which failed to diagnose onl
y a case of cyst associated with chronic pancreatitis depicted by MRCP. We
used a GE Signa Horizon 1.5-T system (20 examinations) and a Siemens Magnet
on Plus 1.5-T machine (four examinations). Eleven patients were operated on
. In all cases, it was possible to identify the cysts, the main pancreatic
duct and the biliary tree, and verify the relationship of the cyst with nei
ghboring organs. Communication of the cyst with the main pancreatic duct wa
s described in five instances, but we cannot be sure that MRCP would have d
epicted all cyst-duct communications. The MRI and MRCP images were confirme
d by surgery in the 11 operated-on cases. The diagnosis of duct alterations
and small pancreatic stones in initial cases of chronic calcifying pancrea
titis may be problematic. Clinical findings are very important data to be c
onsidered in the differential diagnosis of KLP. Together with the clinical
data, MRCP is a very important technique in the diagnostic and therapeutic
decision making of KLP. Standard magnetic resonance is advisable as part of
the examination in all cases. MRCP is not invasive, is reliable if one kno
ws its limitations, and the patient can return at once to his activities. I
t allows the analysis of many variables in one examination, contributing to
better therapy.