Reports on the clinical picture of primary infection with the human herpesv
irus-7 (HHV-7) are scarce. A heterogenous population of 478 patients (1 mon
th-14years) was examined for the presence of an acute HHV-7 infection. A va
riety of clinical pictures can be observed during primary infection with HH
V-7, such as exanthema subitum and mononucleosis-like syndrome. The authors
describe in two children, for the first time, the presentation of HHV-7-in
fection as an acute exacerbation or relapse of a patient's chronic disease.
The hematological changes for the respective clinical presentations during
HHV-7 infection are reported.