Oligohydramnion, renal failure and no pulmonary hypoplasia in glomerulocystic kidney disease

Two newborns with glomerulocystic kidney disease manifesting as late onset oligohydramnion and neonatal anuria, yet without severe respiratory distres s, are presented. They had a similar perinatal course and associated clinic al manifestations. No associated congenital or inherited malformation syndr ome could be defined. Both infants' parents were first degree cousins and b elonged to the same small Bedouin tribe, and neither they nor the infants' siblings had polycystic kidneys or renal insufficiency, pointing to either a possible genetic etiology or a common external toxic exposure.