HORMONE REPLACEMENT THERAPY AND OTHER POTENTIAL TREATMENTS FOR DEMENTIAS

Citation
Wl. Mcbee et al., HORMONE REPLACEMENT THERAPY AND OTHER POTENTIAL TREATMENTS FOR DEMENTIAS, Endocrinology and metabolism clinics of North America, 26(2), 1997, pp. 329
Citations number
85
Categorie Soggetti
Endocrynology & Metabolism
ISSN journal
08898529
Volume
26
Issue
2
Year of publication
1997
Database
ISI
SICI code
0889-8529(1997)26:2<329:HRTAOP>2.0.ZU;2-N
Abstract
The past decade has seen a substantial increase in the number of indiv iduals affected by dementia. Dementia places a tremendous personal and economic burden on millions of patients and caregivers annually. Cons equently, many scientists have been searching for a treatment for deme ntia to avoid the imminent public health crisis that will occur if thi s trend continues. Primary and secondary prevention studies, as well a s animal research, demonstrate the potential for hormone replacement t herapy (HRT) as an efficacious treatment for dementia. Recently. the W omen's Health Initiative-Memory Study began the first randomized, long term clinical trial to test the hypothesized role of HRT at the onset and in the progression of dementia in women. Researchers also are inve stigating the potential of other treatments for dementias, such as non steroidal anti-inflammatory drugs and free radical scavengers.