Women who cannot or choose not to take estrogens do have alternatives;
however, the options are few and unproven in longterm clinical trials
with respect to safety and efficacy. Many available alternative treat
ments may alleviate the symptoms of the menopause, but do not convey l
ong-term protection against osteoporosis and cardiovascular disease. T
his article reviews treatment alternatives to estrogen replacement the
rapy for symptomatic relief.