Effects of cationic micelles on the rate of intramolecular general base-catalyzed reaction of ionized phenyl salicylate with DL-proline

Pseudo-first order rate constants (k(obs)) Obtained for the reaction of ion ized phenyl salicylate (PS-) with anionic DL-proline (Prl(-)) at a constant [NaOH] and [CTABr] (where CTABr represents cetyltrimethylammonium bromide) and 35 degrees C, show a linear increase with increasing total concentrati on of Prl(-). Nucleophilic second-order rate constants (k(n)(obs)) for the reactions of Prl(-) with PS- reveal a nearly 5-fold decrease with the incre ase in [CTABr] from 0.0 to 0.01 M.