Bats, which represent approximately 24% of all known mammalian species, fre
quently act as vectors of lyssaviruses. In particular, insectivorous bats p
lay an important role in the epidemiology of rabies and some rabies-like vi
ruses, while the haematophagous vampire bats are the major wildlife vector
for rabies in Latin America. in contrast, the role of fruit bats (flying fo
xes) in the epidemiology of the recently discovered Australian bat lyssavir
us is only just emerging. Information on the pathogenesis of lyssaviruses i
n bats is scarce. However, in general, mortality in bats infected via a nat
ural route appears to be low, and seroconversion occurs in many of those th
at survive. While transmission of rabies from an infected bat may be via a
bite, other routes are apparently also possible. Methods for the diagnosis
of bat lyssavirus infections in bats and terrestrial mammals (including hum
ans) are similar to the classical procedures for rabies. Measures for the p
revention and control of these diseases are also similar to those for rabie
s, although additional innovative methods have been tested, specifically to
control vampire bat rabies.