Background: Irritable bowel syndrome (IBS) is commonly thought to he associ
ated with psychologic distress. However. in some studies only persons who h
ad sought medical cart: for IBS (IBS patients) showed an increased frequenc
y of psychiatric symptoms, and nonpatients did not differ significantly fro
m normal subjects. Our aims were 1) to estimate the prevalence of IBS in th
e population aged 18-45 years, 2) to find the proportion seeking medical ca
re for IBS, and 3) to compare IBS subjects with normals, and IBS patients w
ith IBS nonpatients with regard to mental health. Methods: Questionnaires o
n IBS symptoms and the General Health Questionnaire (GHQ) were mailed to 50
00 randomly sampled persons aged 18-45 years. The response rate was 58%. Re
sults: IBS was found in 7.4% of the men and 13.3% of the women. Those who h
ad sought medical attention had more severe symptoms. The Likert mean score
on the GHQ was 4.7 (95% confidence interval, 4.4-5.0) points higher for th
e IBS group than for normals (P < 0.001). There was no difference in GHQ sc
ores between IBS patients and nonpatients. Conclusions: The results indicat
e that IBS per se is associated with more psychiatric distress, regardless
of medical care-seeking. Seeking medical care is associated with more sever
e IBS symptoms.