While it is now established that astigmatism is more prevalent in infants a
nd young children than in the adult population, little is known about the f
unctional significance of this astigmatism, especially its role, if any, in
emmetropization and the development of myopia. Manifest refractions (mean
of 16 per subject) were obtained from 245 subjects starting in the first ye
ar, with 6-23 years of regular follow-up. Results showed that infantile ast
igmatism is associated with increased astigmatism and myopia during the sch
ool years. Two possible mechanisms underlying this association are discusse
d: (1) infantile astigmatism disrupts focusing mechanisms; and (2) ocular g
rowth induces astigmatism and myopia. (C) 2000 Elsevier Science Ltd. All ri
ghts reserved.