H. Li et Sc. Yao, SURGICAL-TREATMENT FOR CARCINOMA OF THE ESOPHAGUS IN CHINESE-LANGUAGEPUBLICATIONS, British Journal of Surgery, 84(6), 1997, pp. 855-857
Introduction This review is a meta-analysis of Chinese language public
ations on surgical treatment for oesophageal cancer. Methods Between 1
980 and 1994, 17815 patients had surgery for carcinoma of the oesophag
us. The male:female ratio was 3.9:1 and mean age was 51.9 (range 16-80
) years. Results Mean resectability rate was 86.7 per cent and hospita
l mortality rate was 3.8 per cent. The crude 5-year and 10-year surviv
al rates for all patients were 29.6 and 16.4 per cent respectively. Fo
r patients with stage 0 and stage I tumours, the 5-year survival rate
was 95 and 89 per cent respectively, significantly greater than that f
or those with stage II, III and IV tumours (19.4 per cent, P < 0.01).
The 5-year survival rate of all 2226 patients with tumour resection af
ter radiotherapy was 38.0 per cent. There was no significant differenc
e in survival following combination therapy compared with surgery alon
e. When compared with a report for the interval 1940-1979, there was n
o significant difference in the resectability, hospital mortality or 5
-year survival rates. Conclusion Oesophageal carcinoma remains a disea
se with dismal prognosis but surgery still offers the best chance of l
ong-term survival. Adjuvant therapy has not yet proved an advantage in
terms of survival but can be useful for palliation. Mass screening mi
ght improve survival but only in a population with a high incidence of
oesophageal carcinoma.