Free triiodothyronine (FT3) measurement using an electrochemiluminescence immunoassay in patients with autoantibodies to triiodothyronine

Authors
Semlitsch, G Buchinger, W Reiterer, E Binter, G Rainer, F
Citation
G. Semlitsch et al., Free triiodothyronine (FT3) measurement using an electrochemiluminescence immunoassay in patients with autoantibodies to triiodothyronine, ACT MED AUS, 27(2), 2000, pp. 54-55
Citations number
9
Categorie Soggetti
General & Internal Medicine
Journal title
ACTA MEDICA AUSTRIACA
ISSN journal
03038173 → ACNP
Volume
27
Issue
2
Year of publication
2000
Pages
54 - 55
Database
ISI
SICI code
0303-8173(2000)27:2<54:FT(MUA>2.0.ZU;2-8
Abstract
Thyroid hormone autoantibodies may lead to abnormal values of free triiodot hyronine (FT3) and free thyroxine (FT3) by interference with the radio immu noassay (RIA). We examined thyroid function in six patients with known trii odothyronine-binding autoantibodies using a RIA and an electrochemiluminesc ence immunoassay (ECLIA). FT3 values measured by RIA were spuriously high, ECLIA Measurement of FT3 led to correct values according to the patients th yroid status. We conclude from these results that in patients with triiodot hyronine-binding autoantibodies FT3 measurement by ECLIA is more useful tha n measurement by RIA.