Increased childhood morbidity after measles is short term in urban Bangladesh

Citation
Sm. Akramuzzaman et al., Increased childhood morbidity after measles is short term in urban Bangladesh, AM J EPIDEM, 151(7), 2000, pp. 723-735
Citations number
37
Categorie Soggetti
Envirnomentale Medicine & Public Health","Medical Research General Topics
Journal title
AMERICAN JOURNAL OF EPIDEMIOLOGY
ISSN journal
00029262 → ACNP
Volume
151
Issue
7
Year of publication
2000
Pages
723 - 735
Database
ISI
SICI code
0002-9262(20000401)151:7<723:ICMAMI>2.0.ZU;2-R
Abstract
In a 1995-1996 cohort study in the city of Dhaka, Bangladesh, morbidity in 117 hospitalized and 137 acute measles cases compared with age-matched chil dren without measles (unexposed) was determined by weekly interview for 6 m onths. Compared with unexposed children, there were higher incidences of ho spitalization (adjusted rate ratio (RR) = 3.1, 95% confidence interval (CI) : 1.3, 7.6) and bloody diarrhea (adjusted RR = 2.7, 95% CI: 1.4, 5.1) in ho spital measles cases during the 6 weeks after recruitment. Among community cohorts, there were higher incidences of bloody diarrhea (adjusted RR = 4.1 , 95% CI: 1.1, 14.6), watery diarrhea (adjusted RR = 1.6, 95% CI: 0.9, 2.7) , fast breathing (adjusted RR = 3.8, 95% CI: 2.1, 6.9), and the weekly poin t prevalence of pneumonia (adjusted prevalence ratio = 3.1, 95% CI: 1.0, 9. 8) in measles cases during the same period. All measles cases regained lost weight within about 6 weeks. The prevalence of anergy to seven recall anti gens 6 weeks after recruitment was higher in both hospital (adjusted odds r atio = 2.8, 95% CI: 1.2, 6.4) and community (adjusted odds ratio = 3.1, 95% CI: 1.1, 8.9) measles cases. Morbidity increased during the first 6-8 week s after measles, but the authors found no consistent evidence of longer-ter m morbidity or wasting. The results support recent findings that measles is not associated with increased delayed mortality.