Ad. Sperber et al., Use of the Functional Bowel Disorder Severity Index (FBDSI) in a study of patients with the irritable bowel syndrome and fibromyalgia, AM J GASTRO, 95(4), 2000, pp. 995-998
OBJECTIVE: The purpose of this study was to evaluate the utility of the Fun
ctional Bowel Disorder Severity Index (FBDSI) as a measure of severity of d
isease among patients with the irritable bowel syndrome (IBS) and matched c
ontrols.
METHODS: A total of 75 IBS patients and 69 matched controls completed quest
ionnaires on bowel symptoms, health status, quality of life, psychological
distress, concerns, anxiety, and sense of coherence. All participants also
were tested for fibromyalgia (FS), a functional disorder of the musculoskel
etal system. All participants were administered a questionnaire that includ
ed the FBDSI. On the basis of their responses to the questionnaire, the con
trols were subdivided as healthy controls (n = 48) or IBS nonpatients (n =
21). On the basis of the FS classification, 75 IBS patients were subdivided
as IBS only (n = 50) or IBS and FS combined (n = 25).
RESULTS: The mean FBDSI score was higher for the IBS patients than the cont
rols (100.5 +/- 12.7 and 23.5 +/- 3.9, respectively; p < 0.001). IBS nonpat
ients had an intermediate score of 42.3 +/- 18.0. Patients with both IBS an
d fibromyalgia had the highest mean FBDSI score: 138.8 +/- 31.5. There was
no association between FBDSI and age or gender, bur FBDSI was significantly
associated with other measures of health status.
CONCLUSIONS: An association was found between the FBDSI and IBS patient sta
tus: IBS nonpatients. patients with IBS only, and patients with both IBS an
d fibromyalgia had increasingly severe scores. The results provide support
for the validity of FBDSI as a measure of illness severity in functional ga
strointestinal disorders. (C) 2000 by Am. Cell. of Gastroenterology.