Sc. Wang et al., Effects of alkaline hydrolysis and dynamic coating on the electroosmotic flow in polymeric microfabricated channels, ANALYT CHEM, 72(7), 2000, pp. 1704-1706
Protocols are described for control of the electroosmotic flow in microfabr
icated channels in Vivak copolyester. Alkaline hydrolysis of surface ioniza
ble groups alone or such hydrolysis in combination with dynamic coating wit
h cetyltrimethylammonium bromide (CTAB) is shown to provide reproducible el
ectroosmotic flows. Dynamic coating with CTAB can be used to eliminate elec
troosmosis or to reverse its direction, depending on the concentration empl
oyed.