Disseminated metastasis of neuroblastomatous component in immature mediastinal teratoma: a case report

A 17-year-old man with high levels of serum AFP and hCG was diagnosed as ha ving primary mediastinal GCT. Cisplatin-based chemotherapy decreased the bi omarkers, brit the mass showed further growth. Pathological examination of the resected mass revealed a mixture of immature and mature teratomas. Six months after the surgery the patient died of a dissemination of neuroblasto matous cells, which were similar to those in the immature neural component of the primary tumor: A disseminated metastasis of neuroblastoma in immatur e mediastinal teratoma is a rare complication. Serum NSE can be a useful ma rker in detecting the metastasis.