More than half of adult Americans are overweight or obese, and public healt
h recommendations call for weight loss in those who are overweight with ass
ociated medical conditions or who are obese. However, some controversy exis
ts in the lay press and in the medical literature about the health risks of
obesity. We review briefly the large body of evidence indicating that high
er levels of body weight and body fat are associated with an increased risk
for the development of numerous adverse health consequences. Efforts to pr
event further weight gain in adults at risk for overweight and obesity are
essential. For those whose present or future health is at risk because of t
heir obesity and who are motivated to make lifestyle changes, a recommendat
ion for weight loss is appropriate.