Polypropylene hollow fiber oxygenators: Effect of the sorption of perfluoropolyethers

The introduction of microporous polypropylene hollow fibers in recent years has brought considerable advances to blood oxygenators. However, lifetime and assembly problems are still unresolved. In this work we tried to rate t he oxygen permeation velocity by turning the fibers more hydrophobic throug h the sorption of a perfluorocarbon. Fomblin HC/25, a perfluoropolyether, i s well known for its low surface tension and high affinity for oxygen. Celg ard X10, X20, and X30 commercial hollow fibers were tested. The hollow fibe rs showed high affinity for the perfluoropolyether; swelling was clearly sh own. A new system for the measurement of oxygen permeation velocity was dev eloped. The oxygen transport velocity was not significantly changed after s orption. The Celgard microporous hollow fibers impregnated with perfluoropo lyether showed no water permeation after 2 months of use, reducing one of t he most serious problems in the lifetime of these types of fibers.