N-butyl-2-cyanoacrylate based tissue adhesive, Tisuacryl, was employed as a
nonsuture method for closing wounds in oral surgery. One hundred thirty pa
tients were treated with the adhesive and 30 with suture. The surgical proc
edures were apicectomy, extraction of molars, and mucogingival grafting. Th
e studied product was well tolerated by the tissue and permitted immediate
hemostasis and normal healing of incisions. When Tisuacryl was used as dres
sing material for donor sites and mucosal ulcerations, pain relief was obse
rved.