Oxazole-Carbonyl photocycloadditions: selectivity pattern and synthetic route to erythro alpha-amino, beta-hydroxy ketones

Authors
Griesbeck, AG Fiege, M Lex, J
Citation
Ag. Griesbeck et al., Oxazole-Carbonyl photocycloadditions: selectivity pattern and synthetic route to erythro alpha-amino, beta-hydroxy ketones, CHEM COMMUN, (7), 2000, pp. 589-590
Citations number
15
Categorie Soggetti
Chemistry
Journal title
CHEMICAL COMMUNICATIONS
ISSN journal
13597345 → ACNP
Issue
7
Year of publication
2000
Pages
589 - 590
Database
ISI
SICI code
1359-7345(2000):7<589:OPSPAS>2.0.ZU;2-9
Abstract
The photocycloaddition of aliphatic and aromatic aldehydes with 2,4,5-trime thyloxazole proceeds highly regio- and diastereoselectively to give bicycli c oxetanes; hydrolytic cleavage of these adducts gives selectively erythro alpha-amino, beta-hydroxy methyl ketones.