The development of the stria vascularis in the human cochlea was studied in
step sections of 81 human foetal temporal bones. The stria vascularis prim
ordium can be identified as a ridge of epithelial cells on the lateral wall
of the cochlear duct. The first signs of differentiation appear at the 11t
h week, but it is not until the 17th-18th week that the typical trilaminar
structure is observed. The appearance of similar cells with notched nuclei
in both marginal and mesenchymal layers at this stage suggests the possibil
ity that some of the intermediate cells may be of epithelial origin. By the
21st week, the overall appearance resembles that of the adult structure. T
his occurs 1 week after the opening of the tunnel of Corti, and possibly ma
rks the onset of cochlear function.