Alcohol consumption during methadone maintenance treatment (MMT) often beco
mes a problem. We investigated a group of 68 patients undergoing MMT in our
care. Mean duration of MMT was 50 months. A set of risk factors for proble
matic alcohol use ('alcohol indicators') was set up consisting of patients'
account and laboratory parameters. 52% of patients were positive for these
'alcohol indicators' and 32% of patients fulfilled more severe criteria fo
r alcohol abuse. There was exactly the same proportion of patients with 'al
cohol indicators' at the start of MMT as at follow-up examination. In 79% o
f these patients 'alcohol indicators' were found on both occasions, testify
ing that alcohol problems were a stable trait. While patients without 'alco
hol indicators' showed an improvement of liver parameters over time, those
with 'alcohol indicators' suffered a considerable deterioration, indicating
that the amount of alcohol consumption had increased. Copyright (C) 2000 S
. Karger AG, Basel.