A rare case of a successfully excised intra- and extrathoracic lipoblastoma
of the anterior chest wall in a 13-month-old female infant is reported. Hi
stopathology and cytogenetical analysis established the diagnosis of a lipo
blastoma. The differential diagnosis, histology and cytogenetical evaluatio
n of lipomatous neoplasms are discussed. Karyotypic analysis may be of use
in diagnostically difficult cases owing to the characteristic alterations i
n 18q11-13. A complete resection of lipoblastomas is feasible and advantage
ous with no need for a mutilating radical excision.