Intracardiac thrombosis in a case of Behcet's disease associated with the prothrombin 20210G-A mutation

Thrombosis occurs In 20 to 30% of patients with Behcet's disease (BD), but the precise pathogenic mechanism underlying the thrombotic tendency in thes e patients is not well known. Venous thromboses are commonly located in the lower extremities, but right intracardiac thrombi are extremely ii rare. W e report for the first time on a young patient with ED associated the 20210 G-A prothrombin gene mutation and right intracardiac thrombosis. We suggest that the association of no with this newly recognized prothrombotic geneti c mutation may have contributed to the development of the thrombotic event in this patient. (C) 2000 Ferrata Storti Foundation.