M. Nielen et al., EVALUATION OF 2 COWSIDE TESTS FOR THE DETECTION OF SUBCLINICAL KETOSIS IN DAIRY-COWS, Canadian veterinary journal, 35(4), 1994, pp. 229-232
The goal of this study was to evaluate the sensitivy and specificity o
f two cowside tests for subclinical ketosis in diary cows. The tests u
tilize milk and urine samples, respectively. One hundred and eighty-fi
ve cows, one to sixty days postpartum, were sampled for milk, urine, a
nd blood. Subclinical ketosis was defined with serum beta-hydroxybutyr
ate measurements. The sensitivity and the specificity of both tests at
different beta-hydroxybutyrate levels were estimated. When subclinica
l ketosis was defined at beta-hydroxybutyrate levels of 1.4 mmol/L and
higher, the milk test had sensitivity of 90% and specificity of 96%.
The urine test lacked specificity (values <67%), but sensitivity was 1
00% at beta-hydroxybutyrate levels of 1.4 mmol/L upward.Both the milk
and urine test can be used to monitor subclinical ketosis in a herd. M
ilk testing is preferred, because of the easy obtainability of milk co
mbined with the overall better test characteristics.