Use of magnetic resonance spectroscopy for in vivo evaluation of high-energy phosphate metabolism in normal and abnormal myocardium

P-31- and H-1-nuclear magnetic resonance spectroscopy (MRS) are powerful to ols for studying myocardial energy metabolism. The purpose of this review i s to illustrate how these MRS technique can be risen to study complex bioen ergetic issues in normal and abnormal in vivo myocardium. The results provi de insight into the energetic alterations present in remodeled and hypertro phied myocardium. A detailed understanding of energy metabolism in normal a nd abnormal myocardium may point the way to improved preventive, diagnostic , and therapeutic modalities for left ventricular dysfunction.