Laser in situ keratomileusis following Acanthamoeba keratitis

PURPOSE: Although data regarding reactivation of microbial corneal infectio ns following LASIK is scarce, the use of excimer laser is known to be an ef ficient trigger for the reactivation of herpes simplex keratitis. With this in mind, the use of excimer laser, including LASIK, theoretically places t he cornea at potential risk for reactivation of other microbial infections. Acanthamoeba keratitis is a severe, painful, sight-threatening infection m ost often associated with soft contact lens use. Treatment of Acanthamoeba keratitis is notoriously difficult, and despite prolonged administration of anti-protozoal agents such as polyhexamethylene, propamidine isethionate ( Brolene), and neomycin, recurrence of the keratitis can occur. Postoperativ e reactivation following penetrating keratoplasty performed for visual reha bilitation in patients with previous Acanthamoeba keratitis has been docume nted, and LASIK, when performed on these patients, may raise concerns about the potential risk of reactivation of the infection. METHODS: We report the case of a myopic patient with previous Acanthamoeba keratitis and corneal scarring who underwent LASIK without preoperative ant i-protozoal prophylaxis. RESULTS: During a B-month follow-up period after LASIK, no recurrence of th e infection was noted. CONCLUSION: In our patient who previously suffered from Acanthamoeba kerati tis and underwent LASIK, no reactivation of the infection was seen.