The reaction of 3-nitropyridine with sulfite ions; a pathway to 2,5-disubstituted pyridines

Authors
Bakke, JM Ranes, E Romming, C Sletvold, I
Citation
Jm. Bakke et al., The reaction of 3-nitropyridine with sulfite ions; a pathway to 2,5-disubstituted pyridines, J CHEM S P1, 8, 2000, pp. 1241-1243
Citations number
11
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1
ISSN journal
0300922X → ACNP
Volume
8
Year of publication
2000
Pages
1241 - 1243
Database
ISI
SICI code
0300-922X(2000)8:<1241:TRO3WS>2.0.ZU;2-P
Abstract
The reaction of 3-nitropyridine with an aqueous solution of sodium sulfite gave the disodium salt of 5-(N-sulfohydroxyamino)pyridine-2-sulfonic acid ( 2) which on treatment with an acidic ion exchange resin gave 5-hydroxyamino pyridine-2-sulfonic acid (3). The yield of 3 from 3-nitropyridine was 63%. The structures of the products were verified by X-ray analysis.