Frequency of Escherichia coli strains producing the cytotoxic necrotizing factor (CNF1) in nosocomial urinary tract infections

Authors
Landraud, L Gauthier, M Fosse, T Boquet, P
Citation
L. Landraud et al., Frequency of Escherichia coli strains producing the cytotoxic necrotizing factor (CNF1) in nosocomial urinary tract infections, LETT APPL M, 30(3), 2000, pp. 213-216
Citations number
21
Categorie Soggetti
Biotecnology & Applied Microbiology",Microbiology
Journal title
LETTERS IN APPLIED MICROBIOLOGY
ISSN journal
02668254 → ACNP
Volume
30
Issue
3
Year of publication
2000
Pages
213 - 216
Database
ISI
SICI code
0266-8254(200003)30:3<213:FOECSP>2.0.ZU;2-F
Abstract
The presence of cytotoxic necrotizing factor 1 (CNF1), together with variou s associated virulence factors (alpha-haemolysin, P-, S- and A-fimbriae), w as screened in 175 uropathogenic Escherichia. coli strains isolated from ho spitalized adult patients. The cnf1 gene was detected in 30% of the selecte d strains independently of the severity of the clinical urinary infection. A significant association between CNF1, haemolytic activity and the product s of the pap/sfa genes was found. However, CNF1 appeared not to play a majo r role in nosocomial E. coli urinary tract infections..