Synthesis of some 2, 6-disubstituted 4-amidopyridines and -thioamidopyridines, and their antimycobacterial and photosynthesis-inhibiting activity

Authors
Miletin, M Hartl, J Dolezal, M Odlerova, Z Kralova, K Machacek, M
Citation
M. Miletin et al., Synthesis of some 2, 6-disubstituted 4-amidopyridines and -thioamidopyridines, and their antimycobacterial and photosynthesis-inhibiting activity, MOLECULES, 5(3), 2000, pp. 208-218
Citations number
10
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
MOLECULES
ISSN journal
14203049 → ACNP
Volume
5
Issue
3
Year of publication
2000
Pages
208 - 218
Database
ISI
SICI code
1420-3049(200003)5:3<208:SOS264>2.0.ZU;2-Q
Abstract
A group of 26 new 2-halogeno-6-alkylsulfanyl- and 2,6-bis-alkylsulfanyl-4-a midopyridines and corresponding thioamidopyridines was synthesised, Some of the amidopyridines and all thioamidopyridines were tested for their antimy cobacterial activity against atypical mycobacterial strains. Promising phot osynthesis-inhibiting activity was also found for some of the amidopyridine s.