Escherichia coli B121: A useful biocatalyst for the synthesis of purine nucleosides

Authors
Rogert, MC Martinez, N Porro, S Lewkowicz, E Iribarren, A
Citation
Mc. Rogert et al., Escherichia coli B121: A useful biocatalyst for the synthesis of purine nucleosides, MOLECULES, 5(3), 2000, pp. 535-536
Citations number
2
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
MOLECULES
ISSN journal
14203049 → ACNP
Volume
5
Issue
3
Year of publication
2000
Pages
535 - 536
Database
ISI
SICI code
1420-3049(200003)5:3<535:ECBAUB>2.0.ZU;2-F
Abstract
E. coli BL21 cells were able to synthesize several purine nucleosides from pyrimidine ones. Kinetics and yields of this reaction showed a strong depen dence on pH, temperature, reagent concentrations and weight of wet cell pas te. Yields over 90% were reached in the synthesis of adenosine.