I analyse the density perturbations in a cosmological model with a scalar f
ield coupled to ordinary matter, such as one obtains in string theory and i
n conformally transformed scalar-tensor theories. The spectrum of multipole
s on the last scattering surface and the power spectrum at the present epoc
h are compared with observations to derive bounds on the coupling constant
and on the exponential potential slope. It is found that the acoustic peaks
and the power spectrum are strongly sensitive to the model parameters. The
models that best fit the galaxy spectrum and satisfy the cluster abundance
normalization have field energy density Omega(phi)similar or equal to 0.05
-0.15 and a scalefactor expansion law a similar to t(p), p similar or equal
to 0.67-0.69.